陈金阳

|  个人简介

陈金阳，博士，副教授，硕士生导师，中共党员。2017年6月博士毕业于武汉大学分析化学专业，获理学博士学位。2017年6月入职KY开元集团。

主要从事分析化学专业教学与纳米生物传感方向研究工作。先后主持国家自然科学基金、湖北省自然科学基金等科研项目7项，发表SCI论文30余篇，获授权国家发明专利1项。曾获“刘道玉创造研究奖”、“唐敖庆化学奖”、“KY开元集团优秀班主任”等奖励和荣誉称号。

|  教学及人才培养

1. 主讲《分析化学》《分析化学实验》等本科生课程和《材料技术与表征》《现代分析测试技术》等研究生课程

2. 承担本科生学位论文及综合化学实验指导工作

3. 担任分析化学学科研究生导师

 |  主要科研课题

1. 主持：国家自然科学基金青年基金项目（22004031），2021-2023年，24万元

2. 主持：湖北省自然科学基金面上项目（2023AFB996），2023-2025年，5万元

3. 主持：湖北省自然科学基金青年项目（2019CFB182），2019-2021年，5万元

4. 主持：湖北省教育厅科学研究计划项目（Q20182504），2018-2019年，2万元

|  代表性论文论著 

1. Yuhui Shang, Xinying Liang, Yali Liu, Jinyang Chen*, Rolling circle extension-initiated self-priming loop-mediated isothermal amplification and generative nanosignal transduction for single-tube APE1 sensing, Sensors and Actuators B: Chemical, 2026, 467, 140578.（TOP期刊，IF：8.3）

2. Chunjiao Qi, Yali Liu, Yu Yang, Yuhui Shang, Jinyang Chen*, Ultrafast green gelation reaction for power-free glucose sensing and rapid hyperglycemia screening, Sensors and Actuators B: Chemical, 2026, 458, 139845.（TOP期刊，IF：8.3）

3. Yuhui Shang, Xinying Liang, Yali Liu, Jinyang Chen*, Rolling circle amplification-triggered loop-mediated isothermal amplification and in-situ fluorescence signal transduction for one-tube APE1 sensing, Analytica Chimica Acta, 2026, 1421, 346069.（TOP期刊，IF：6.1）

4. Jintao Chen, Yuhui Shang, Yu Yang , Yali Liu , Jinyang Chen*, Palindrome design-guided “single-flap-double-duties” and “dual-enzymes-quadruple-cycles” enabled nano-signal amplification for customized FEN1 sensing, Talanta, 2026, 297, 128642.（TOP期刊，IF：6.7）

5. Jintao Chen, Yuhui Shang, Yu Yang, Yali Liu, Jinyang Chen*, Palindrome-Mediated Isothermal Cascade DNA Amplification and Effortless Nano-Signal Transduction for One-Pot and Ultrasensitive miRNA Sensing, Analytical Chemistry, 2025, 97, 21012-21020.（TOP期刊，自然指数期刊，IF：7.3）

6. Ting Zhu, Yu Yang, Yuhui Shang , Yali Liu , Jinyang Chen*, All-in-one prepared highly stable fluorescent copper nanocluster composite for point-of-care sensing of tetracycline, Analytica Chimica Acta, 2025, 1377, 344688.（TOP期刊，IF：6.1）

7. Shasha Zeng, Jintao Chen, Chunjiao Qi, Guobin Mao, Yuhui Shang, Yu Yang, Jinyang Chen*, Self-priming isothermal polymerization engineered in-situ copper nanoparticles generation for one-tube biomarkers sensing, Analytica Chimica Acta, 2025, 1351, 343903.（TOP期刊，IF：6.1）

8. Chunjiao Qi, Jintao Chen, Yuhui Shang, Yu Yang, Kangyan Wang, Jinyang Chen*, Target-triggered ultrafast chondroitin gelation enabled power-free and point-of-care bioassays. Analytical Chemistry, 2024, 96, 17781-17788.（TOP期刊，自然指数期刊，IF：7.3）

9. Shasha Zeng, Jintao Chen, Chunjiao Qi, Yuhui Shang, Yu Yang, Jinyang Chen*, Ligation initiated self-priming isothermal polymerization enablednano-signal amplification for APE1 sensing and logical unlocking. Sensors and Actuators B: Chemical, 2024, 420, 136467.（TOP期刊，IF：8.0）

10. Ting Zhu, Jinyang Chen*, Shasha Zeng, Jintao Chen, and Chunjiao Qi, Highly stable fluorescent-traffic-light sensor for point-of-care detection of tetracycline. ACS Sensors, 2023, 8, 4272-4280.（TOP期刊，IF：8.9）

11. Qingli Chai, Jinyang Chen*, Shasha Zeng, Ting Zhu, Jintao Chen, Chunjiao Qi, Guobin Mao, Yucheng Liu, Closed cyclic DNA machine for sensitive logic operation and APE1 detection. Small, 2023, 19, 2207736.（TOP期刊，IF：15.15）

12. Shasha Zeng, Jinyang Chen*, Qingli Chai, Ting Zhu, Guobin Mao, Label-free and low-background FEN1 sensing based on cleavage-induced ligation of bifunctional dumbbell DNA and in-situ signal readout. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 290, 122295.（IF：4.3）

13. Yanyun Zou, Jinyang Chen*, Qingli Chai, Ting Zhu, Shasha Zeng, Yucheng Liu, Stimuliresponsivecolorimetric sensor based on bifunctional pyrophosphate-triggered controlled releaseand enhancing activity of CoOOH nanozyme. Sensors and Actuators B: Chemical, 2022, 369, 132215.（TOP期刊，IF：9.2）

14. Ting Zhu, Jinyang Chen*, Qingli Chai, Shasha Zeng, Yucheng Liu, Stable and sensitivesensor for alkaline phosphatase based on target-triggered wavelength tuning of fluorescent coppernanoclusters. Analytica Chimica Acta, 2022, 1232, 340453.（TOP期刊，IF：6.9）

15. Yanyun Zou, Qingli Chai, Ting Zhu, Xiaoxiao Yu, Guobin Mao, Ningxing Li, Jinyang Chen*, Guosong Lai, Simultaneously colorimetric detection and effective removal of mercury ion based on facile preparation of novel and green enzyme mimic. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 266, 120410.（IF：4.8）

16. Yuqi Wan, Qingli Chai, Yanyun Zou, Guobin Mao, Jinyang Chen*, A versatile fluorescent nanobeacon lighted by DNA-templated copper nanoparticles and the application in isothermal amplification detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 262, 120102.（IF：4.8）

17. Haoyu Chen, Li Wu, Yuqi Wan, Lulu Huang, Ningxing Li, Jinyang Chen*, Guosong Lai, One-step rapid synthesis of fluorescent silicon nanodots for a hydrogen peroxide-related sensitive and versatile assay based on the inner filter effect. Analyst, 2019, 144, 4006-4012.（IF：3.9）

18. Jinyang Chen, Xinghu Ji, Zhike He*, Smart composite reagent composed of double-stranded DNA-templated copper nanoparticle and SYBR Green I for hydrogen peroxide related biosensing. Analytical Chemistry, 2017, 89, 3988-3995.（TOP期刊，自然指数期刊，IF：6.7）

19. Jinyang Chen, XinghuJi, Philip Tinnefeld, Zhike He*, Multifunctional dumbbell-shaped DNA-templated selective formation of fluorescent silver nanoclusters or copper nanoparticles for sensitive detection of biomolecules. ACS Applied Materials & Interfaces, 2016, 8, 1786-1794.（TOP期刊，IF：8.3）

20. Jinyang Chen, Yucheng Liu, XinghuJi, Zhike He*, Target-protecting dumbbell molecular probe against exonucleases digestion for sensitive detection of ATP and streptavidin. Biosensors and Bioelectronics, 2016, 83, 221-228.（TOP期刊，IF：10.7）

|  发明专利

1. 陈金阳；柴青丽；万雨琦，一种基于双链DNA模板荧光纳米铜的荧光分子信标及其制备方法和应用，专利号：ZL202110337265.0，授权公告日：2023-3-15.

|  主要荣誉及获奖 

1. 2020年、2022年学校教学优秀奖，KY开元集团，2021.3；2023.3

2. 2019-2020学年度优秀班主任，KY开元集团，2020.10

(更新时间：2025年9月10日)